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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1881644Generated: November 1, 2026

1-[5-(3,4-dichlorophenyl)-4-hydroxy-1-methyl-1H-pyrazol-3-yl]ethanone → 5-{[(2-{1-[5-(3,4-dichlorophenyl)-4-hydroxy-1-methyl-1H-pyrazol-3-yl]ethylidene}hydrazino)-carbonothioyl]amino}-2-thiophenecarboxylic acid

https://huagongshe.com/reaction/1881644

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[5-(3,4-dichlorophenyl)-4-hydroxy-1-methyl-1H-pyrazol-3-yl]ethanoneHCID 60206780—
Reactant5-Hydrazinocabonothioylamino-2-thiophenecarboxylic acidHCID 86014497—
Product5-{[(2-{1-[5-(3,4-dichlorophenyl)-4-hydroxy-1-methyl-1H-pyrazol-3-yl]ethylidene}hydrazino)-carbonothioyl]amino}-2-thiophenecarboxylic acidHCID 72359997—

Reaction Steps

From 1-[5-(3,4-dichlorophenyl)-4-hydroxy-1-methyl-1H-pyrazol-3-yl]ethanone (40.0 mg, 0.14 mmol) and 5-hydrazinocabonothioylamino-2-thiophenecarboxylic acid (33.9 mg, 0.14 mmol), the desired product was obtained in the same manner as in Synthetic Example 114 as a pale yellow solid (62.2 mg, yield 92%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08318796B2
Source datasetuspto-grants-2012_11
ORD IDord-d13f37731dee4f21bf5226b86a333b01
Source noteuspto-grants-2012_11