Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1881647Generated: November 2, 2026

2-(3,4-Dichlorophenyl)-3-hydroxy-4-(methylcarbonyl)thiophene → 4-{[(2-{1-[5-(3,4-Dichlorophenyl)-4-hydroxy-3-thienyl]ethylidene}hydrazino)-carbonothioyl]amino}-2-chlorobenzoic acid

https://huagongshe.com/reaction/1881647

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3,4-Dichlorophenyl)-3-hydroxy-4-(methylcarbonyl)thiopheneHCID 44207288—
Reactant4-Hydrazinocabonothioylamino-2-chlorobenzoic acidHCID 86014498—
Product4-{[(2-{1-[5-(3,4-Dichlorophenyl)-4-hydroxy-3-thienyl]ethylidene}hydrazino)-carbonothioyl]amino}-2-chlorobenzoic acidHCID 72360075—

Reaction Steps

From 2-(3,4-dichlorophenyl)-3-hydroxy-4-methylcarbonylthiophene (50 mg, 0.17 mmol) and 4-hydrazinocabonothioylamino-2-chlorobenzoic acid (42.8 mg, 0.17 mmol), the desired product was obtained in the same manner as in Synthetic Example 50 as a pale yellow solid (61.1 mg, yield 68%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08318796B2
Source datasetuspto-grants-2012_11
ORD IDord-9cb30fc0a242467ab7e4c46002180c45
Source noteuspto-grants-2012_11