HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 5-[Bis(methyloxy)methyl]-3-bromo-2-methylpyridine 1-oxide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | m-Chloroperbenzoic acid | HCID 70297 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | 5-[Bis(methyloxy)methyl]-3-bromo-2-methylpyridine | HCID 67427076 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 5-[Bis(methyloxy)methyl]-3-bromo-2-methylpyridine 1-oxide | HCID 67428542 | — |
Reaction Steps
m-CPBA (242 mg, 1.052 mmol) was added to a suspension of 5-[bis(methyloxy)methyl]-3-bromo-2-methylpyridine (129.5 mg, 0.526 mmol) and NaHCO3 (133 mg, 1.579 mmol) in DCM (5 ml). The mixture was stirred at room temperature overnight. To the resulting white suspension was added DCM and 1N NaOH. The organic phase was extracted twice,
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08318940B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-9de1d027737c4d9fa3cd4959679e90a0 |
| Source note | uspto-grants-2012_11 |