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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1881791Generated: November 1, 2026

4-Methoxy-3-methylbenzoic Acid → HCID 11680744, compound

https://huagongshe.com/reaction/1881791

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methoxy-3-methylbenzoic AcidHCID 2759583—
Reactant1-Aminoindane, (S)-HCID 7000084—
ProductHCID 11680744HCID 1168074463%

Reaction Steps

Prepared in a similar manner to example 4 using 4-methoxy-3-methylbenzoic acid and (S)-2,3-dihydro-1H-inden-1-amine. Yield 63%. 1HNMR (500 MHz, dMSO): δ 1.94-1.99 (m, 1H), 2.17 (s, 3H), 2.41-2.46 (m, 1H), 2.82-2.87 (m, 1H), 2.96-3.01 (m, 1H), 3.83 (s, 3H), 5.53-5.57 (dd, 1H), 6.98-6.99 (d, 1H), 7.16-7.23 (m, 3H), 7.26-7.27 (m, 1H), 7.75-7.80 (m, 2H), 8.54-8.55 (d, 1H). MS (M+H, 282).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08318947B2
Source datasetuspto-grants-2012_11
ORD IDord-1dce0b18baf647b9b2a6f59fe1e60e28
Source noteuspto-grants-2012_11