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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1882265Generated: October 31, 2026

5-(3-(ethylsulfonyl)phenyl)-3-methyl-9H-pyrido[2,3-b]indol-8-ol → HCID 58880180, compound

https://huagongshe.com/reaction/1882265

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(3-(ethylsulfonyl)phenyl)-3-methyl-9H-pyrido[2,3-b]indol-8-olHCID 58880081—
Reactant3-chloro-5-(3-(ethylsulfonyl)phenyl)-8-methoxy-9H-pyrido[2,3-b]indol-8-olHCID 86612633—
ProductHCID 58880180HCID 58880180—

Reaction Steps

The title compound was prepared from Compound 217 by using an analogous procedure to that outlined in the preparation of Compound 157. 1H NMR (400 MHz, Methanol-d4) δ 8.35 (s, 1H) 8.15 (m, 1H) 8.07 (m, 1H) 7.97 (m, 1H) 7.88 (t, J=8.0 Hz, 1H) 7.66 (s, 1H) 7.23 (d, J=8.36 Hz, 1H) 7.16 (d, J=8.36 Hz, 1H) 4.44 (t, J=5.8 Hz, 2H) 3.72 (t, J=8.0 Hz, 2H) 3.43 (q, J=7.32 Hz, 2H) 3.03 (s, 6H) 2.41 (m, 2H) 1.34 (t, J=7.32 Hz, 3H). [M+H] calc'd for C24H27ClN3O3S, 472; found, 472.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08318939B2
Source datasetuspto-grants-2012_11
ORD IDord-0433ee6ac2a842b88c39fd77887bb0f2
Source noteuspto-grants-2012_11