HCID 58880180, compound → 4-(2-(3-chloro-5-(3-(ethylsulfonyl)phenyl)-9H-pyrido[2,3-b]indol-8-yloxy)ethyl)morpholine

Participants

Role	Name	HCID	Charge
Reactant	HCID 58880180	HCID 58880180	—
Reactant	3-(5-(3-(ethylsulfonyl)phenyl)-3-methyl-9H-pyrido[2,3-b]indol-8-yloxy)-N,N-dimethylpropan-1-amine	HCID 58880181	—
Product	4-(2-(3-chloro-5-(3-(ethylsulfonyl)phenyl)-9H-pyrido[2,3-b]indol-8-yloxy)ethyl)morpholine	HCID 58880196	—

Reaction Steps

The title compound was prepared from Compound 218 by using an analogous procedure to that outlined in the preparation of Compound 205. 1H NMR (400 MHz, Methanol-d4) δ 8.12 (s, 1H) 8.00 (m, 1H) 7.92 (m, 1H) 7.74 (t, J=7.84 Hz, 1H) 7.64 (s, 1H) 7.09 (m, 1H) 7.02 (m, 1H) 6.84 (s, 1H) 4.40 (t, J=5.0 Hz, 2H) 4.11 (br, 4H) 3.80 (br, 4H) 3.55 (t, J=5.0 Hz, 2H) 3.30 (q, J=7.32 Hz, 2H) 1.27 (t, J=7.32 Hz, 3H). [M+H] calc'd for C25H27ClN3O4S, 500; found, 500.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08318939B2
Source dataset	uspto-grants-2012_11
ORD ID	ord-4ccd39a8a92f441781af9742436388ee
Source note	uspto-grants-2012_11