Lawesson's reagent → HCID 86644387, compound

Participants

Reaction Steps

To N-phenyl-3,3-bis(phenylthio)propionamide (0.90 g) were added Lawesson's reagent (2.0 g) and 1,4-dioxane (20 mL), and the mixture was heated to reflux for 1.5 hours. The reaction mixture was left to cool to room temperature, and then concentrated under reduced pressure. The residue was isolated and purified by medium pressure preparative liquid chromatography (YAMAZEN SI-40B, hexane:ethyl acetate=3:1) to obtain N-phenyl-3,3-bis(phenylthio)thiopropionamide (0.69 g) as an orange oil.

Provenance & Evidence