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HRID1882589

反应详情

EQUATION

反应方程式

HRID 1882589 的结构方程式

REACTANTS

反应物

3
结构：NC1CCN(c2ccccn2)CC1
HCID10197934

1-(2-Pyridinyl)-4-piperidinamine

C10H15N3

结构：N[C@@H]1CCN(c2nc(NCC(c3ccccc3)c3ccccc3)c3ncn([C@@H]4C[C@H](NC(=O)COCc5ccccc5)[C@@H](O)[C@H]4O)c3n2)C1.O=C(O)C(F)(F)F
HCID66630722

未命名化合物

结构：CCC(=O)N[C@H]1C[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(Cl)nc32)[C@H](O)[C@@H]1O
HCID86622630

未命名化合物

2 次

PRODUCTS

生成物

1
结构：CCC(=O)N[C@H]1C[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(NC4CCN(c5ccccn5)CC4)nc32)[C@H](O)[C@@H]1O.O=C(O)C(F)(F)F
HCID66631014

未命名化合物

PROCEDURE

实验过程

This compound is prepared analogously to N-{(1S,2R,3S,4R)-4-[2-((R)-3-amino-pyrrolidin-1-yl)-6-(2,2-diphenyl-ethylamino)-purin-9-yl]-2,3-dihydroxy-cyclopentyl}-2-benzyloxy-acetamide trifluoroacetate Example 1 (Step 2) by replacing 2-benzyloxy-N-{(1S,2R,3S,4R)-4-[2-chloro-6-(2,2-diphenyl-ethylamino)-purin-9-yl]-2,3-dihydroxy-cyclopentyl}-acetamide with N-{(1S,2R,3S,4R)-4-[2-chloro-6-(2,2-diphenyl-ethylamino)-purin-9-yl]-2,3-dihydroxy-cyclopentyl}-propionamide (Intermediate J) and by replacing (3R)-3-aminopyrrolidine with 3,4,5,6-tetrahydro-2H-[1,2′]bipyridinyl-4-ylamine. (MH+ 331.7)