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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 188284Generated: October 30, 2026

Acetic Acid → 2-{3-Methoxy-6-[3-methoxy-5-methylaminomethyl-4-(2-trimethylsilanyl-ethoxymethoxy)-phenyl]-pyridazin-4-yl}-indole-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/188284

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantMethanolHCID 887—
ReactantSodium ionHCID 923—
ReactantMethylamineHCID 6329—
ReactantTetrahydrofuranHCID 8028—
ReactantCyano-borohydrideHCID 498716—
Reactant2-{6-[3-Formyl-5-methoxy-4-(2-trimethylsilanyl-ethoxymethoxy)-phenyl]-3-methoxy-pyridazin-4-yl}-indole-1-carboxylic acid tert-butyl esterHCID 86612060—
Product2-{3-Methoxy-6-[3-methoxy-5-methylaminomethyl-4-(2-trimethylsilanyl-ethoxymethoxy)-phenyl]-pyridazin-4-yl}-indole-1-carboxylic acid tert-butyl esterHCID 68638496—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-732aa88349404d52975dcc6870af678d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)