HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1882910Generated: November 2, 2026
Diethyl aluminum cyanide → HCID 57254707, compound
https://huagongshe.com/reaction/1882910
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Diethyl aluminum cyanide | HCID 16686413 | — |
| Reactant | HCID 57263809 | HCID 57263809 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 57254707 | HCID 57254707 | 26.7% |
Reaction Steps
8α,9α-Epoxycholest-5-en-3β-ol (200mg) is dissolved in dichloromethane and the solution is cooled to 0° C. 1.5 ml of a diethylaluminumcyanide-solution (1 M in toluene) is added dropwise. After addition, the reaction mixture is warmed to room temperature and stirred for additional 18 hours. After basic work-up and column chromatography, cholesta-5,8,14-triene-3β-ol (51 mg) is isolated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06759400B2 |
|---|
| Source dataset | uspto-grants-2004_07 |
|---|
| ORD ID | ord-96df104ca1da4abebf75122331a68531 |
|---|
| Source note | uspto-grants-2004_07 |
|---|
