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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1882964Generated: October 30, 2026

Hydrochloric Acid → HCID 9956765, compound

https://huagongshe.com/reaction/1882964

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant2-MethylcyclopentanoneHCID 14265—
ReactantSodium cyanoborohydrideHCID 5003444—
ReactantHCID 21906397HCID 21906397—
ProductHCID 9956765HCID 9956765158.2%

Reaction Steps

Using a similar procedure to that described in Example 9-C, N-(5-chloropyridin-2-yl)-2-[(pyrrolidine-3-yloxycarbonyl)amino]benzamide trifluoroacetate (100 mg, 0.211 mmol), 2-methylcyclopentanone (0.112 mL, 1.05 mmol), and sodium cyanoborohydride (53 mg, 0.84 mmol) yielded, after treatment with HCl, 80 mg (80%) of the title compound as the hydrochloride salt.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06759414B2
Source datasetuspto-grants-2004_07
ORD IDord-a5461e43182e49cd918ea1673dfb4e89
Source noteuspto-grants-2004_07