HCID 17925573, compound → HCID 21906245, compound

HRID 1883035Notes

Reaction equation

HRID 1883035 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([NH:8][C:9](=[O:18])[C:10]2[CH:15]=[C:14]([CH2:16][CH3:17])[CH:13]=[CH:12][CH:11]=2)=[N:6][CH:7]=1.[C:19]([O:23][C:24]([N:26]1[CH2:31][CH2:30][CH:29]([C:32]2[O:37]C(=O)C3C=C(CC)C=CC=3[N:33]=2)[CH2:28][CH2:27]1)=[O:25])([CH3:22])([CH3:21])[CH3:20]>>[C:19]([O:23][C:24]([N:26]1[CH2:31][CH2:30][CH:29]([C:32]([NH:33][C:11]2[CH:12]=[CH:13][C:14]([CH2:16][CH3:17])=[CH:15][C:10]=2[C:9]([NH:8][C:5]2[CH:4]=[CH:3][C:2]([Cl:1])=[CH:7][N:6]=2)=[O:18])=[O:37])[CH2:28][CH2:27]1)=[O:25])([CH3:22])([CH3:20])[CH3:21]

Participants

3

Reactant 2

HCID 17925573HCID 17925573, compoundHCID 131724473HCID 131724473, compound

Product 1

HCID 21906245HCID 21906245, compound

Procedure

Using methods substantially equivalent to those described in Example 51-D, 2-(1-tert-butoxycarbonylpiperidin-4-ylcarbonyl)amino)-N-(5-chloropyridin-2-yl)-5-ethylbenzamide (1.27 g, 47%) was prepared from 2-[(1-tert-butoxycarbonylpiperidin-4-yl)-6-ethyl-4H-3,1-benzoxazin-4-one.

Sources & evidence

ORD record
ord-252290e184a54feb9b50c431c8c2d6a1
Source dataset
uspto-grants-2004_07
Patent number
US06759414B2

Reaction notes

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