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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1883171Generated: November 1, 2026

Water → HCID 23510333, compound

https://huagongshe.com/reaction/1883171

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantSodium borohydrideHCID 4311764—
ReactantHCID 23510482HCID 23510482—
SolventIsopropanolHCID 3776—
ProductHCID 23510333HCID 2351033380.8%

Reaction Steps

To a solution of (1H-pyrrol-2-yl)(3-quinolyl)methanol (40.0 mg) in 2-propanol (3 mL) was added sodium borohydride (33.9 mg), and the mixture was refluxed for one hour. To the mixture was added water, and the mixture was concentrated. The residue was separated using water and ethyl acetate, and the organic layer was dried, filtered, and concentrated. The residue was purified by silica gel column chromatography to give 2-(3-quinolylmethyl)-1H-pyrrole (30.0 mg, 75%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06759429B2
Source datasetuspto-grants-2004_07
ORD IDord-b0e6c19112ab4aa398fd77f2d5353f69
Source noteuspto-grants-2004_07