HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 23510333, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | HCID 23510482 | HCID 23510482 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 23510333 | HCID 23510333 | 80.8% |
Reaction Steps
To a solution of (1H-pyrrol-2-yl)(3-quinolyl)methanol (40.0 mg) in 2-propanol (3 mL) was added sodium borohydride (33.9 mg), and the mixture was refluxed for one hour. To the mixture was added water, and the mixture was concentrated. The residue was separated using water and ethyl acetate, and the organic layer was dried, filtered, and concentrated. The residue was purified by silica gel column chromatography to give 2-(3-quinolylmethyl)-1H-pyrrole (30.0 mg, 75%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06759429B2 |
| Source dataset | uspto-grants-2004_07 |
| ORD ID | ord-b0e6c19112ab4aa398fd77f2d5353f69 |
| Source note | uspto-grants-2004_07 |