反应详情

Following General Procedure A and using AlCl3 (3.7 g, 27.5 mmol), CH2Cl2 (40 mL), propionyl chloride (2.4 mL, 27.5 mmol), and 6-methoxy-1,1,4,4-tetramethyl-1,2,3,4-tetrahydro-naphthalene (Intermediate 2, 5.0 g, 22.9 mmol) in CH2Cl2 (10 mL) at ambient temperature for 1.5 h followed by recrystallization from Et2O, the title compound was obtained as a white solid (5.4 g, 86%).

1. customat ambient temperature
2. customfor 1.5 h
3. customfollowed by recrystallization from Et2O