Hydrochloric Acid → HCID 131724487, compound

Participants

Reaction Steps

A solution of diol 86 and conc. HCl (1 equiv) in methanol is degassed by bubbling nitrogen through it for 30 min. To this is added 10% palladized charcoal (5 wt. percent). The resulting mixture is shaken on a Parr apparatus under 50 psi of hydrogen gas for 16 h. The mixture is then filtered and the filtrate evaporated. The residue is flushed several times with chloroform to drive off traces of methanol. The crude product is carried on without further purification.

Provenance & Evidence