Ruthenium → HCID 131724488, compound

Participants

Reaction Steps

2.83 g of (1R,2R)-N-(2-diphenylphosphanylbenzyl)-N′-[2-diphenylphosphanyl-5-(4-vinylbenzyloxy)benzyl]cyclohexan-1,2-diamine (3.5 mmol, 9.4% stabiliser) are refluxed for 1 hour under protective gas with 3.36 g of dichlorotetrakis(dimethyl sulfoxide)ruthenium(II) (7 mmol) in 200 ml of absolute toluene. During the reaction, 120 mg of a yellowish solid precipitate out, which can be identified as a ruthenium-stabiliser complex. Once the reaction solution has been filtered, the solvent is removed in a rotary evaporator and the product separated by column chromatography on silica gel (isohexane/ethyl acetate 2:1). In order to isolate the product, the chromatographic fractions should not be evaporated to dryness, but instead combined with isohexane once the eluent has largely been removed. As a result, the product precipitates as a yellow/orange powder at a yield of 1.86 g (55%).

Provenance & Evidence