6-Bromo-1-hexanol → HCID 23506709, compound

HRID 1883528Notes

Reaction equation

HRID 1883528 reaction equation
[ClH:1].NC1N=C(CCCCC[CH2:14][C:15]([NH:17][C:18]2[CH:23]=[C:22]([C:24]([CH3:27])([CH3:26])[CH3:25])[C:21]([OH:28])=[C:20]([C:29]([CH3:32])([CH3:31])[CH3:30])[CH:19]=2)=[O:16])C=C(C)C=1.Cl.[NH2:35][C:36]1[N:41]=[C:40]([CH2:42][CH2:43][CH2:44][CH2:45]NC(=O)C2C=C(O)C=C(C)C=2O)[CH:39]=[C:38]([CH3:58])[CH:37]=1.BrCCCCCCO>>[ClH:1].[NH2:35][C:36]1[N:41]=[C:40]([CH2:42][CH2:43][CH2:44][CH2:45][CH2:14][C:15]([NH:17][C:18]2[CH:19]=[C:20]([C:29]([CH3:31])([CH3:32])[CH3:30])[C:21]([OH:28])=[C:22]([C:24]([CH3:25])([CH3:26])[CH3:27])[CH:23]=2)=[O:16])[CH:39]=[C:38]([CH3:58])[CH:37]=1

Participants

4

Reactant 3

HCID 779706-Bromo-1-hexanolHCID 23506728HCID 23506728, compoundHCID 69890290HCID 69890290, compound

Product 1

HCID 23506709HCID 23506709, compound

Procedure

The experimental protocol used is the same as that described for compound 16, the trimethylsilylated derivative of 5-chloro-1-pentanol (prepared according to J. Org. Chem., (1988), 53 (12), 2732-7) replacing the trimethylsilyl derivative of 6-bromo-1-hexanol. Off-white solid. Melting point: 101-103° C.

Sources & evidence

ORD record
ord-6eddce63c0cc4c5ab333df53e6601ebd
Source dataset
uspto-grants-2004_07
Patent number
US06762176B1

Reaction notes

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