3,3-Dimethylbutylamine → HCID 131724496, compound

HRID 1883557Notes

Reaction equation

HRID 1883557 reaction equation
[CH3:1][C:2]([CH3:7])([CH3:6])[CH2:3][CH2:4][NH2:5].[CH:8]([O:10][C@@H:11]1[C@@H:15]([O:16][CH:17]=[O:18])[C@H:14]([N:19]2[CH:27]=[N:26][C:25]3[C:20]2=[N:21][C:22]([NH:34][CH2:35][CH2:36][C:37]2[N:38]=[CH:39][N:40]([CH3:42])[CH:41]=2)=[N:23][C:24]=3NC(CC)CC)[O:13][C@@H:12]1[C:43]1[O:47][N:46]=[C:45]([CH2:48][CH3:49])[CH:44]=1)=[O:9]>>[CH:17]([O:16][C@@H:15]1[C@@H:11]([O:10][CH:8]=[O:9])[C@@H:12]([C:43]2[O:47][N:46]=[C:45]([CH2:48][CH3:49])[CH:44]=2)[O:13][C@H:14]1[N:19]1[CH:27]=[N:26][C:25]2[C:20]1=[N:21][C:22]([NH:34][CH2:35][CH2:36][C:37]1[N:38]=[CH:39][N:40]([CH3:42])[CH:41]=1)=[N:23][C:24]=2[NH:5][CH2:4][CH2:3][C:2]([CH3:7])([CH3:6])[CH3:1])=[O:18]

Participants

3

Reactant 2

HCID 197093,3-DimethylbutylamineHCID 131724497HCID 131724497, compound

Product 1

HCID 131724496HCID 131724496, compound

Procedure

Example 7 was prepared in an analogous manner to Example 4 using 3,3-dimethylbutylamine (0.006 g, 0.056 mmol) and 2-(1-methyl-1H-imidazol-4-yl)ethylamine (0.035 g, 0.28 mmol; generated as in Example 5) at 90° C. for 5 days. The title compound was afforded after freeze-drying as a brown solid (0.007 g). LC/MS SYSTEM A Rt=3.80 mins, m/z=540 MH+.

Sources & evidence

ORD record
ord-9e4a6be9dbaf4e0e872becb2c61290bc
Source dataset
uspto-grants-2004_07
Patent number
US06762170B1

Reaction notes

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