Bromine → HCID 22597763, compound

HRID 1883576Notes

Reaction equation

HRID 1883576 reaction equation
[CH3:1][O:2][C:3]1[CH:11]=[C:10]([CH:12]([CH3:14])[CH3:13])[CH:9]=[CH:8][C:4]=1[C:5]([OH:7])=[O:6].[Br:15]Br>C(Cl)(Cl)Cl>[Br:15][C:9]1[C:10]([CH:12]([CH3:14])[CH3:13])=[CH:11][C:3]([O:2][CH3:1])=[C:4]([CH:8]=1)[C:5]([OH:7])=[O:6]

Participants

4

Reactant 2

HCID 24408BromineHCID 126137372-Methoxy-4-(propan-2-yl)benzoic acid

Product 1

HCID 22597763HCID 22597763, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent2×

Procedure

To a solution of 2-methoxy-4-iso-propyl benzoic acid (7.0 g. 36.0 mmol) in chloroform (100 ml) was added bromine (1.86 ml) in chloroform (20 ml) dropwise. The reaction was stirred at room temperature overnight. Evaporation in vacuo afforded an oil (9.27 g).

Workup

  1. customEvaporation in vacuo

Sources & evidence

ORD record
ord-21529fa3e6bb4f22a5d9f04f7621d684
Source dataset
uspto-grants-2004_07
Patent number
US06762192B2

Reaction notes

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