HCID 86759492, compound → HCID 131724500, compound

Participants

Reaction Steps

To a solution of t-butyl-4-nitro-3-[(2-hydroxy-N-methylacetylamino)methyl]benzoate (7.92 g, 23.15 mmole) in CH3OH (25 mL) and EtOAc (25 mL) in a Parr hydrogenation flask was added 10% Pd/C (0.20 g). The contents were shaken on a Parr shaker under H2 (50 psi) for 4 hours. The suspension was filtered through celite, concentrated under vacuum and washed with Et2O to afford the title compound as a light orange foam which was used without further purification: MS (ES) m/e 295 (M+H)+.

Provenance & Evidence