HCID 23508344, compound → HCID 69758887, compound

Participants

Reaction Steps

To a solution of N-[(2-nitro-5-{N-methyl-N-[(1-methylindol-2-yl)methyl]carbamoyl}phenyl)methyl]-N-methyl(phenylmethoxy)carboxamide (6.1 g, 12.2 mmole) in CH3OH (50 mL) contained in a Parr hydrogenation flask was added a 0.75 g of 10% Pd/C. The contents were shaken on a Parr shaker under H2 (50 psi) for 6 hours. The suspension was filtered through celite and concentrated under vacuum. Purification on silica [CHCl3/CH3OH (containing 5% NH4OH), 9:1] afforded the title compound (3.40 g, 83%) as a viscous yellow oil: MS (ES) m/e 337 (M+H)+.

Provenance & Evidence