Dimethylsulphamoyl chloride → HCID 23508570, compound

Participants

Reaction Steps

The procedure of Example 88 was repeated, except that 120 mg of 4′-hydroxy-4-nitro-2-biphenylcarbonitrile was used in place of N-(4′-hydroxybiphenyl-4-yl)methanesulfonamide, and 0.430 ml of N,N-dimethylsulfamoyl chloride was used in place of sulfamoyl chloride. The resulting crude product was purified by TLC (using a 16:1 mixture of chloroform and acetone as the developing solvent) to obtain 97 mg of 2′-cyano-4′-nitrobiphenyl-4-yl N,N-dimethylsulfamate.

Provenance & Evidence