Water → HCID 23508388, compound

Participants

Reaction Steps

100 mg of 4-[N-(4-benzyloxybenzyl)amino]phenol was dissolved in 4 ml of pyridine, and 2 ml of acetic anhydride was added thereto, followed by stirring at room temperature for 2 hours. After water was added to the reaction mixture, the product was extracted with ethyl acetate. The organic layer was washed with 5% hydrochloric acid and a saturated aqueous solution of sodium hydrogen carbonate, and dried over anhydrous sodium sulfate. After the solvent was distilled off, the resulting crude product was purified by TLC (using chloroform as the developing solvent) to obtain 114 mg of 4-[N-acetyl-N-(4-benzyloxy-benzyl)amino]phenyl acetate.

Provenance & Evidence