HCID 23508388, compound → HCID 23508566, compound

HRID 1883673Notes

Reaction equation

HRID 1883673 reaction equation
[C:1]([O:4][C:5]1[CH:10]=[CH:9][C:8]([N:11]([C:27](=[O:29])[CH3:28])[CH2:12][C:13]2[CH:18]=[CH:17][C:16]([O:19]CC3C=CC=CC=3)=[CH:15][CH:14]=2)=[CH:7][CH:6]=1)(=[O:3])[CH3:2]>C(O)C>[C:1]([O:4][C:5]1[CH:6]=[CH:7][C:8]([N:11]([C:27](=[O:29])[CH3:28])[CH2:12][C:13]2[CH:14]=[CH:15][C:16]([OH:19])=[CH:17][CH:18]=2)=[CH:9][CH:10]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 1

HCID 23508388HCID 23508388, compound

Product 1

HCID 23508566HCID 23508566, compoundYield 87.8%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The procedure of Preparation Example 9 was repeated, except that 400 mg of 4-[N-acetyl-N-(4-benzyloxybenzyl)amino]phenyl acetate was used in place of 4-[N-(4-benzyloxybenzyl)-N-methylsulfonylamino]phenyl methanesulfonate, and 6 ml of ethanol was used in place of dioxane. Thus, there was obtained 270 mg of 4-[N-acetyl-N-(4-hydroxybenzyl)amino]phenyl acetate.

Workup

  1. customThe procedure of Preparation Example 9

Sources & evidence

ORD record
ord-a9eb8f86a24a4feba6adc6c2ad93f2c1
Source dataset
uspto-grants-2004_07
Patent number
US06762205B1

Reaction notes

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