4-(2,6-Dimethyl-piperidin-1-ylmethyl)-phenylamine → HCID 178468590, compound

HRID 1883778Notes

Reaction equation

HRID 1883778 reaction equation
C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[CH:11]=2)[C:6](=[C:18](OCC)[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[C:5]1=[O:28])(=O)C.[CH3:29][CH:30]1[CH2:35][CH2:34][CH2:33][CH:32]([CH3:36])[N:31]1[CH2:37][C:38]1[CH:44]=[CH:43][C:41]([NH2:42])=[CH:40][CH:39]=1>>[CH3:36][CH:32]1[CH2:33][CH2:34][CH2:35][CH:30]([CH3:29])[N:31]1[CH2:37][C:38]1[CH:39]=[CH:40][C:41]([NH:42]/[C:18](=[C:6]2\[C:5](=[O:28])[NH:4][C:12]3[C:7]\2=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[CH:11]=3)/[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)=[CH:43][CH:44]=1

Participants

3

Reactant 2

HCID 31539974-(2,6-Dimethyl-piperidin-1-ylmethyl)-phenylamineHCID 685275611-Acetyl-3-(1-ethoxy-1-phenylmethylene)-6-ethoxycarbonyl-2-indolinone

Product 1

HCID 178468590HCID 178468590, compound

Procedure

Prepared from 1-acetyl-3-(1-ethoxy-1-phenylmethylene)-6-ethoxycarbonyl-2-indolinone and 4-[(2,6-dimethyl-piperidin-1-yl)-methyl]-aniline Rf value: 0.6 (silica gel, methylene chloride/ethanol=5:1) C32H35N3O3

Sources & evidence

ORD record
ord-535e1970e69f483c85d91aca9095ec09
Source dataset
uspto-grants-2004_07
Patent number
US06762180B1

Reaction notes

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