4-[N-(2-dimethylamino-ethyl)-N-methylsulphonyl-amino]-aniline → HCID 178468601, compound

HRID 1883782Notes

Reaction equation

HRID 1883782 reaction equation
C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[CH:11]=2)[C:6](=[C:18](OCC)[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[C:5]1=[O:28])(=O)C.[CH3:29][N:30]([CH3:45])[CH2:31][CH2:32][N:33]([S:41]([CH3:44])(=[O:43])=[O:42])[C:34]1[CH:39]=[CH:38][C:37]([NH2:40])=[CH:36][CH:35]=1>>[CH3:29][N:30]([CH3:45])[CH2:31][CH2:32][N:33]([C:34]1[CH:35]=[CH:36][C:37]([NH:40]/[C:18](=[C:6]2\[C:5](=[O:28])[NH:4][C:12]3[C:7]\2=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[CH:11]=3)/[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)=[CH:38][CH:39]=1)[S:41]([CH3:44])(=[O:43])=[O:42]

Participants

3

Reactant 2

HCID 225696634-[N-(2-dimethylamino-ethyl)-N-methylsulphonyl-amino]-anilineHCID 685275611-Acetyl-3-(1-ethoxy-1-phenylmethylene)-6-ethoxycarbonyl-2-indolinone

Product 1

HCID 178468601HCID 178468601, compound

Procedure

Prepared from 1-acetyl-3-(1-ethoxy-1-phenylmethylene)-6-ethoxycarbonyl-2-indolinone and N-(2-dimethylamino-ethyl)-N-methylsulphonyl-p-phenylenediamine Rf value: 0.3 (aluminium oxide, methylene chloride/ethanol=40:1) C29H32N4O5S

Sources & evidence

ORD record
ord-610cc990b4614edfafdf63b7fc8a1e21
Source dataset
uspto-grants-2004_07
Patent number
US06762180B1

Reaction notes

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