4-(Pyrrolidin-1-ylmethyl)aniline → HCID 178468588, compound

HRID 1883791Notes

Reaction equation

HRID 1883791 reaction equation
C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[CH:11]=2)[C:6](=[C:18](OCC)[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[C:5]1=[O:28])(=O)C.[N:29]1([CH2:34][C:35]2[CH:41]=[CH:40][C:38]([NH2:39])=[CH:37][CH:36]=2)[CH2:33][CH2:32][CH2:31][CH2:30]1>>[N:29]1([CH2:34][C:35]2[CH:41]=[CH:40][C:38]([NH:39]/[C:18](=[C:6]3\[C:5](=[O:28])[NH:4][C:12]4[C:7]\3=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[CH:11]=4)/[C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)=[CH:37][CH:36]=2)[CH2:33][CH2:32][CH2:31][CH2:30]1

Participants

3

Reactant 2

HCID 7768524-(Pyrrolidin-1-ylmethyl)anilineHCID 685275611-Acetyl-3-(1-ethoxy-1-phenylmethylene)-6-ethoxycarbonyl-2-indolinone

Product 1

HCID 178468588HCID 178468588, compound

Procedure

Prepared from 1-acetyl-3-(1-ethoxy-1-phenylmethylene)-6-ethoxycarbonyl-2-indolinone and 4-(pyrrolidin-1-yl-methyl)-aniline Rf value: 0.1 (silica gel, methylene chloride/ethanol=5:1) C29H29N3O3

Sources & evidence

ORD record
ord-10b887f458b44b2494363d0fda597f51
Source dataset
uspto-grants-2004_07
Patent number
US06762180B1

Reaction notes

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