HRID1883793

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID22569697

N-(4-Aminophenyl)-2-(dimethylamino)-N-methylacetamide

C11H17N3O

结构：CCOC(=O)c1ccc2c(c1)N(C(C)=O)C(=O)C2=C(OCC)c1ccccc1

HCID68527561

Ethyl 1-acetyl-3-(ethoxyphenylmethylene)-2,3-dihydro-2-oxo-1H-indole-6-carboxylate

C22H21NO5

PRODUCTS

生成物

$结构：CCOC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN(C)C)cc1)c1ccccc1$

HCID178468602

未命名化合物

PROCEDURE

实验过程

Prepared from 1-acetyl-3-(1-ethoxy-1-phenylmethylene)-6-ethoxycarbonyl-2-indolinone and N-dimethylaminomethylcarbonyl-N-methyl-p-phenylenediamine Rf value: 0.1 (silica gel, methylene chloride/ethanol=10:1) C29H30N4O4

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-fd35dfa686aa4384b7d776fce22abda6
来源数据集: uspto-grants-2004_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06762180B1
来源说明: uspto-grants-2004_07

反应 SMILES

C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[CH:11]=2)[C:6](=[C:18](OCC)[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[C:5]1=[O:28])(=O)C.[CH3:29][N:30]([CH2:32][C:33]([N:35]([CH3:43])[C:36]1[CH:41]=[CH:40][C:39]([NH2:42])=[CH:38][CH:37]=1)=[O:34])[CH3:31]>>[CH3:31][N:30]([CH2:32][C:33]([N:35]([C:36]1[CH:37]=[CH:38][C:39]([NH:42]/[C:18](=[C:6]2\[C:5](=[O:28])[NH:4][C:12]3[C:7]\2=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[CH:11]=3)/[C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=2)=[CH:40][CH:41]=1)[CH3:43])=[O:34])[CH3:29]