N-(4-aminophenyl)-2-(dimethylamino)-N-methylAcetamide → HCID 178468602, compound

HRID 1883793Notes

Reaction equation

HRID 1883793 reaction equation
C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[CH:11]=2)[C:6](=[C:18](OCC)[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[C:5]1=[O:28])(=O)C.[CH3:29][N:30]([CH2:32][C:33]([N:35]([CH3:43])[C:36]1[CH:41]=[CH:40][C:39]([NH2:42])=[CH:38][CH:37]=1)=[O:34])[CH3:31]>>[CH3:31][N:30]([CH2:32][C:33]([N:35]([C:36]1[CH:37]=[CH:38][C:39]([NH:42]/[C:18](=[C:6]2\[C:5](=[O:28])[NH:4][C:12]3[C:7]\2=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[CH:11]=3)/[C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=2)=[CH:40][CH:41]=1)[CH3:43])=[O:34])[CH3:29]

Participants

3

Reactant 2

HCID 22569697N-(4-aminophenyl)-2-(dimethylamino)-N-methylAcetamideHCID 685275611-Acetyl-3-(1-ethoxy-1-phenylmethylene)-6-ethoxycarbonyl-2-indolinone

Product 1

HCID 178468602HCID 178468602, compound

Procedure

Prepared from 1-acetyl-3-(1-ethoxy-1-phenylmethylene)-6-ethoxycarbonyl-2-indolinone and N-dimethylaminomethylcarbonyl-N-methyl-p-phenylenediamine Rf value: 0.1 (silica gel, methylene chloride/ethanol=10:1) C29H30N4O4

Sources & evidence

ORD record
ord-fd35dfa686aa4384b7d776fce22abda6
Source dataset
uspto-grants-2004_07
Patent number
US06762180B1

Reaction notes

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