4-(Piperidin-1-ylmethyl)aniline → HCID 178468580, compound

HRID 1883795Notes

Reaction equation

HRID 1883795 reaction equation
C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[CH:11]=2)[C:6](=[C:18](OCC)[CH2:19][CH3:20])[C:5]1=[O:24])(=O)C.[N:25]1([CH2:31][C:32]2[CH:38]=[CH:37][C:35]([NH2:36])=[CH:34][CH:33]=2)[CH2:30][CH2:29][CH2:28][CH2:27][CH2:26]1>>[N:25]1([CH2:31][C:32]2[CH:33]=[CH:34][C:35]([NH:36]/[C:18](=[C:6]3\[C:5](=[O:24])[NH:4][C:12]4[C:7]\3=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[CH:11]=4)/[CH2:19][CH3:20])=[CH:37][CH:38]=2)[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30]1

Participants

3

Reactant 2

HCID 8461504-(Piperidin-1-ylmethyl)anilineHCID 68529175HCID 68529175, compound

Product 1

HCID 178468580HCID 178468580, compound

Procedure

Prepared from 1-acetyl-3-(1-ethoxy-1-ethyl-methylene)-6-ethoxycarbonyl-2-indolinone and 4-(piperidin-1-yl-methyl)-aniline Rf value: 0.9 (silica gel, methylene chloride/ethanol=5:1) C26H31N3O3

Sources & evidence

ORD record
ord-37dc396bf6084a17a0bf590f8de32f82
Source dataset
uspto-grants-2004_07
Patent number
US06762180B1

Reaction notes

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