4-[N-(2-dimethylamino-ethyl)-N-methylsulphonyl-amino]-aniline → HCID 178468582, compound

HRID 1883796Notes

Reaction equation

HRID 1883796 reaction equation
C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[CH:11]=2)[C:6](=[C:18](OCC)[CH2:19][CH3:20])[C:5]1=[O:24])(=O)C.[CH3:25][N:26]([CH3:41])[CH2:27][CH2:28][N:29]([S:37]([CH3:40])(=[O:39])=[O:38])[C:30]1[CH:35]=[CH:34][C:33]([NH2:36])=[CH:32][CH:31]=1>>[CH3:25][N:26]([CH3:41])[CH2:27][CH2:28][N:29]([C:30]1[CH:31]=[CH:32][C:33]([NH:36]/[C:18](=[C:6]2\[C:5](=[O:24])[NH:4][C:12]3[C:7]\2=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[CH:11]=3)/[CH2:19][CH3:20])=[CH:34][CH:35]=1)[S:37]([CH3:40])(=[O:39])=[O:38]

Participants

3

Reactant 2

HCID 225696634-[N-(2-dimethylamino-ethyl)-N-methylsulphonyl-amino]-anilineHCID 68529175HCID 68529175, compound

Product 1

HCID 178468582HCID 178468582, compound

Procedure

Prepared from 1-acetyl-3-(1-ethoxy-1-ethyl-methylene)-6-ethoxycarbonyl-2-indolinone and N-(2-dimethylamino-ethyl)-N-methylsulphonyl-p-phenylenediamine Rf value: 0.3 (silica gel, methylene chloride/ethanol=5:1) C25H32N4O5S

Sources & evidence

ORD record
ord-184a32e1e8584005ace0db55d52eade1
Source dataset
uspto-grants-2004_07
Patent number
US06762180B1

Reaction notes

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