n-(3-Dimethylamino-propyl)-n-acetyl-p-phenylenediamine → methyl (3Z)-3-[[4-[acetyl-[3-(dimethylamino)propyl]amino]anilino]-phenylmethylidene]-2-oxo-1H-indole-6-carboxylate
Reaction equation
C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH3:16])=[O:14])[CH:11]=2)[C:6](=[C:17](OCC)[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[C:5]1=[O:27])(=O)C.[CH3:28][N:29]([CH3:44])[CH2:30][CH2:31][CH2:32][N:33]([C:41](=[O:43])[CH3:42])[C:34]1[CH:39]=[CH:38][C:37]([NH2:40])=[CH:36][CH:35]=1>>[CH3:44][N:29]([CH3:28])[CH2:30][CH2:31][CH2:32][N:33]([C:34]1[CH:39]=[CH:38][C:37]([NH:40]/[C:17](=[C:6]2\[C:5](=[O:27])[NH:4][C:12]3[C:7]\2=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH3:16])=[O:14])[CH:11]=3)/[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[CH:36][CH:35]=1)[C:41](=[O:43])[CH3:42]Participants
3
Procedure
Prepared from 1-acetyl-3-(1-ethoxy-1-phenylmethylene)-6-methoxycarbonyl-2-indolinone and N-(3-dimethylamino-propyl)-N-acetyl-p-phenylenediamine Rf value: 0.5 (aluminium oxide, methylene chloride/methanol=20:1) C30H32N4O4
Sources & evidence
- ORD record
- ord-ae479447027f4d9d82a5bc9840819c30
- Source dataset
- uspto-grants-2004_07
- Patent number
- US06762180B1
Reaction notes
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