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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1883802Generated: October 29, 2026

n-Methylaminocarbonylmethyl-n-methylsulphonyl-p-phenylenediamine → methyl (3Z)-3-[[4-[[2-(methylamino)-2-oxoethyl]-methylsulfonylamino]anilino]-phenylmethylidene]-2-oxo-1H-indole-6-carboxylate

https://huagongshe.com/reaction/1883802

Reaction equation

Participants

RoleNameHCIDCharge
Reactantn-Methylaminocarbonylmethyl-n-methylsulphonyl-p-phenylenediamineHCID 23507077—
Reactant1-Acetyl-3-(1-ethoxy-1-phenylmethylene)-6-methoxycarbonyl-2-indolinoneHCID 66685972—
Productmethyl (3Z)-3-[[4-[[2-(methylamino)-2-oxoethyl]-methylsulfonylamino]anilino]-phenylmethylidene]-2-oxo-1H-indole-6-carboxylateHCID 178485782—

Reaction Steps

Prepared from 1-acetyl-3-(1-ethoxy-1-phenylmethylene)-6-methoxycarbonyl-2-indolinone and N-methylaminocarbonylmethyl-N-methylsulphonyl-p-phenylenediamine Rf value: 0.5 (silica gel, methylene chloride/methanol=10:1) C27H26N4O6S

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06762180B1
Source datasetuspto-grants-2004_07
ORD IDord-273360baac964e52995273551582b2a2
Source noteuspto-grants-2004_07