4-Amino-benzylidene-hydantoin → HCID 178497132, compound
Reaction equation
C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH3:16])=[O:14])[CH:11]=2)[C:6](=[C:17](OCC)[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[C:5]1=[O:27])(=O)C.[NH:28]1[C:32](=[CH:33][C:34]2[CH:40]=[CH:39][C:37]([NH2:38])=[CH:36][CH:35]=2)[C:31](=[O:41])[NH:30][C:29]1=[O:42]>>[NH:28]1[C:32](=[CH:33][C:34]2[CH:40]=[CH:39][C:37]([NH:38]/[C:17](=[C:6]3\[C:5](=[O:27])[NH:4][C:12]4[C:7]\3=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH3:16])=[O:14])[CH:11]=4)/[C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)=[CH:36][CH:35]=2)[C:31](=[O:41])[NH:30][C:29]1=[O:42]Participants
3
Procedure
Prepared from 1-acetyl-3-(1-ethoxy-1-phenylmethylene)-6-methoxycarbonyl-2-indolinone and 4-((imidazolidin-2,4-dion-5-ylidene)-methyl)-aniline Rf value: 0.4 (silica gel, methylene chloride/methanol=10:1) C27H20N4O5
Sources & evidence
- ORD record
- ord-8e26333e02394bf3820fd7ca41923cf7
- Source dataset
- uspto-grants-2004_07
- Patent number
- US06762180B1
Reaction notes
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