1-Acetyl-3-(1-ethoxy-1-phenylmethylene)-6-methoxycarbonyl-2-indolinone → HCID 178497135, compound

HRID 1883813Notes

Reaction equation

HRID 1883813 reaction equation
C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH3:16])=[O:14])[CH:11]=2)[C:6](=[C:17](OCC)[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[C:5]1=[O:27])(=O)C.[NH:28]1[CH:32]=[C:31]([CH2:33][CH2:34][C:35]2[CH:41]=[CH:40][C:38]([NH2:39])=[CH:37][CH:36]=2)[N:30]=[CH:29]1>>[NH:28]1[CH:32]=[C:31]([CH2:33][CH2:34][C:35]2[CH:41]=[CH:40][C:38]([NH:39]/[C:17](=[C:6]3\[C:5](=[O:27])[NH:4][C:12]4[C:7]\3=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH3:16])=[O:14])[CH:11]=4)/[C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)=[CH:37][CH:36]=2)[N:30]=[CH:29]1

Participants

3

Reactant 2

HCID 666859721-Acetyl-3-(1-ethoxy-1-phenylmethylene)-6-methoxycarbonyl-2-indolinoneHCID 178507547HCID 178507547, compound

Product 1

HCID 178497135HCID 178497135, compound

Procedure

Prepared from 1-acetyl-3-(1-ethoxy-1-phenylmethylene)-6-methoxycarbonyl-2-indolinone and 4-(2-(imidazol-4-yl)-ethyl)-aniline Rf value: 0.4 (silica gel, methylene chloride/methanol=5:1) C28H24N4O3

Sources & evidence

ORD record
ord-5236f0c494d54c76aa8a6e504edbad6e
Source dataset
uspto-grants-2004_07
Patent number
US06762180B1

Reaction notes

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