HRID1883824

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2760930

tert-Butyl (4-aminophenyl)acetate

C12H17NO2

结构：CCOC(=O)c1ccc2c(c1)N(C(C)=O)C(=O)C2=C(OCC)c1ccccc1

HCID68527561

Ethyl 1-acetyl-3-(ethoxyphenylmethylene)-2,3-dihydro-2-oxo-1H-indole-6-carboxylate

C22H21NO5

PRODUCTS

生成物

$结构：CCOC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(CC(=O)OC(C)(C)C)cc1)c1ccccc1$

HCID178468587

未命名化合物

PROCEDURE

实验过程

Prepared from 1-acetyl-3-(1-ethoxy-1-phenylmethylene)-6-ethoxycarbonyl-2-indolinone and tert.butyl 4-aminophenylacetate Rf value: 0.5 (aluminium oxide, ethyl acetate) C30H30N2O5

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-67fd84cb6aa04f54bd4aefef87450134
来源数据集: uspto-grants-2004_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06762180B1
来源说明: uspto-grants-2004_07

反应 SMILES

C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[CH:11]=2)[C:6](=[C:18](OCC)[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[C:5]1=[O:28])(=O)C.[NH2:29][C:30]1[CH:35]=[CH:34][C:33]([CH2:36][C:37]([O:39][C:40]([CH3:43])([CH3:42])[CH3:41])=[O:38])=[CH:32][CH:31]=1>>[C:40]([O:39][C:37]([CH2:36][C:33]1[CH:34]=[CH:35][C:30]([NH:29]/[C:18](=[C:6]2\[C:5](=[O:28])[NH:4][C:12]3[C:7]\2=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[CH:11]=3)/[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)=[CH:31][CH:32]=1)=[O:38])([CH3:43])([CH3:41])[CH3:42]