Benzoic acid, 4-amino-, 1,1-dimethylethyl ester → HCID 178468581, compound

HRID 1883825Notes

Reaction equation

HRID 1883825 reaction equation
C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[CH:11]=2)[C:6](=[C:18](OCC)[CH2:19][CH3:20])[C:5]1=[O:24])(=O)C.[C:25]([O:29][C:30]([C:32]1[CH:38]=[CH:37][C:35]([NH2:36])=[CH:34][CH:33]=1)=[O:31])([CH3:28])([CH3:27])[CH3:26]>>[C:25]([O:29][C:30]([C:32]1[CH:33]=[CH:34][C:35]([NH:36]/[C:18](=[C:6]2\[C:5](=[O:24])[NH:4][C:12]3[C:7]\2=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[CH:11]=3)/[CH2:19][CH3:20])=[CH:37][CH:38]=1)=[O:31])([CH3:28])([CH3:26])[CH3:27]

Participants

3

Reactant 2

HCID 233272Benzoic acid, 4-amino-, 1,1-dimethylethyl esterHCID 68529175HCID 68529175, compound

Product 1

HCID 178468581HCID 178468581, compound

Procedure

Prepared from 1-acetyl-3-(1-ethoxy-1-ethylmethylen)-6-ethoxycarbonyl-2-indolinone and 4-tert.butoxycarbonyl-aniline Rf value: 0.4 (aluminium oxide, methylene chloride/ethanol=20:1) C25H28N2O5

Sources & evidence

ORD record
ord-94e45d6c23304b6d84a74cce0afa9507
Source dataset
uspto-grants-2004_07
Patent number
US06762180B1

Reaction notes

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