HCID 15933353, compound → HCID 178497129, compound

HRID 1883841Notes

Reaction equation

HRID 1883841 reaction equation
C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH3:16])=[O:14])[CH:11]=2)[C:6](=[C:17](OCC)[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[C:5]1=[O:27])(=O)C.[CH:28]1([CH2:34][C:35]2[CH:41]=[CH:40][C:38]([NH2:39])=[CH:37][CH:36]=2)[CH2:33][CH2:32][CH2:31][CH2:30][CH2:29]1>>[C:28]1(=[CH:34][C:35]2[CH:36]=[CH:37][C:38]([NH:39]/[C:17](=[C:6]3\[C:5](=[O:27])[NH:4][C:12]4[C:7]\3=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH3:16])=[O:14])[CH:11]=4)/[C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)=[CH:40][CH:41]=2)[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33]1

Participants

3

Reactant 2

HCID 15933353HCID 15933353, compoundHCID 666859721-Acetyl-3-(1-ethoxy-1-phenylmethylene)-6-methoxycarbonyl-2-indolinone

Product 1

HCID 178497129HCID 178497129, compound

Procedure

Prepared from 1-acetyl-3-(1-ethoxy-1-phenylmethylene)-6-methoxycarbonyl-2-indolinone and 4-(cyclohexyl-methyl)-aniline (Eur. J. Med. Chem. Chim. Ther. 1992, 27, 537-544) Rf value: 0.6 (silica gel, methylene chloride/methanol=10:1) C30H30N2O3

Sources & evidence

ORD record
ord-c8b443b59faf4bd08964e2c51347b3e4
Source dataset
uspto-grants-2004_07
Patent number
US06762180B1

Reaction notes

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