HRID1883854

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID22569644

N-(4-Aminophenyl)-N-methyl-1-piperidineacetamide

C14H21N3O

结构：CCOC(=C1C(=O)N(C(C)=O)c2cc(C(=O)OC)ccc21)c1ccccc1

HCID66685972

未命名化合物

PRODUCTS

生成物

$结构：COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCCCC2)cc1)c1ccccc1$

HCID178497197

未命名化合物

PROCEDURE

实验过程

Prepared from 1-acetyl-3-(1-ethoxy-1-phenylmethylene)-6-methoxycarbonyl-2-indolinone and N-(piperidin-1-yl-methylcarbonyl)-N-methyl-p-phenylenediamine Rf value: 0.5 (silica gel, methylene chloride/methanol=9:1) C31H32N4O4

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-3ac207315fc244c2870353ddc2945817
来源数据集: uspto-grants-2004_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06762180B1
来源说明: uspto-grants-2004_07

反应 SMILES

C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH3:16])=[O:14])[CH:11]=2)[C:6](=[C:17](OCC)[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[C:5]1=[O:27])(=O)C.[N:28]1([CH2:34][C:35]([N:37]([CH3:45])[C:38]2[CH:43]=[CH:42][C:41]([NH2:44])=[CH:40][CH:39]=2)=[O:36])[CH2:33][CH2:32][CH2:31][CH2:30][CH2:29]1>>[N:28]1([CH2:34][C:35]([N:37]([C:38]2[CH:39]=[CH:40][C:41]([NH:44]/[C:17](=[C:6]3\[C:5](=[O:27])[NH:4][C:12]4[C:7]\3=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH3:16])=[O:14])[CH:11]=4)/[C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)=[CH:42][CH:43]=2)[CH3:45])=[O:36])[CH2:33][CH2:32][CH2:31][CH2:30][CH2:29]1