HRID1883856

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID22569533

未命名化合物

HCID66685972

未命名化合物

PRODUCTS

产物

HCID178497198

未命名化合物

PROCEDURE

实验过程

Prepared from 1-acetyl-3-(1-ethoxy-1-phenylmethylene)-6-methoxycarbonyl-2-indolinone and N-((4-benzyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-p-phenylenediamine Rf value: 0.5 (silica gel, methylene chloride/methanol=9:1) C37H37N5O4

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-03a9d0253dc84c4a96134d23cad764cd
来源数据集: uspto-grants-2004_07
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US06762180B1
来源说明: uspto-grants-2004_07

反应SMILES

C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH3:16])=[O:14])[CH:11]=2)[C:6](=[C:17](OCC)[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[C:5]1=[O:27])(=O)C.[CH2:28]([N:35]1[CH2:40][CH2:39][N:38]([CH2:41][C:42]([N:44]([CH3:52])[C:45]2[CH:50]=[CH:49][C:48]([NH2:51])=[CH:47][CH:46]=2)=[O:43])[CH2:37][CH2:36]1)[C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1>>[CH2:28]([N:35]1[CH2:36][CH2:37][N:38]([CH2:41][C:42]([N:44]([C:45]2[CH:46]=[CH:47][C:48]([NH:51]/[C:17](=[C:6]3\[C:5](=[O:27])[NH:4][C:8]4[C:7]\3=[CH:12][CH:11]=[C:10]([C:13]([O:15][CH3:16])=[O:14])[CH:9]=4)/[C:18]3[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=3)=[CH:49][CH:50]=2)[CH3:52])=[O:43])[CH2:39][CH2:40]1)[C:29]1[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=1