HCID 23507189, compound → HCID 178497180, compound

HRID 1883858Notes

Reaction equation

HRID 1883858 reaction equation
C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH3:16])=[O:14])[CH:11]=2)[C:6](=[C:17](OCC)[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[C:5]1=[O:27])(=O)C.[CH3:28][N:29]([CH3:44])[CH2:30][CH2:31][N:32]([C:36]1[CH:42]=[CH:41][C:39]([NH2:40])=[CH:38][C:37]=1[Br:43])[C:33](=[O:35])[CH3:34]>>[CH3:44][N:29]([CH3:28])[CH2:30][CH2:31][N:32]([C:36]1[CH:42]=[CH:41][C:39]([NH:40]/[C:17](=[C:6]2\[C:5](=[O:27])[NH:4][C:12]3[C:7]\2=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH3:16])=[O:14])[CH:11]=3)/[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[CH:38][C:37]=1[Br:43])[C:33](=[O:35])[CH3:34]

Participants

3

Reactant 2

HCID 23507189HCID 23507189, compoundHCID 666859721-Acetyl-3-(1-ethoxy-1-phenylmethylene)-6-methoxycarbonyl-2-indolinone

Product 1

HCID 178497180HCID 178497180, compound

Procedure

Prepared from 1-acetyl-3-(1-ethoxy-1-phenylmethylene)-6-methoxycarbonyl-2-indolinone and 4-(N-(2-dimethylamino-ethyl)-N-acetyl-amino)-3-bromo-aniline Rf value: 0.6 (silica gel, methylene chloride/methanol=5:1) C29H29BrN4O4

Sources & evidence

ORD record
ord-d45b967b29cc44d4930582c77281de19
Source dataset
uspto-grants-2004_07
Patent number
US06762180B1

Reaction notes

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