4-(5-Methyl-1H-imidazol-4-yl)aniline → HCID 178497128, compound

HRID 1883859Notes

Reaction equation

HRID 1883859 reaction equation
C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH3:16])=[O:14])[CH:11]=2)[C:6](=[C:17](OCC)[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[C:5]1=[O:27])(=O)C.[CH3:28][C:29]1[NH:33][CH:32]=[N:31][C:30]=1[C:34]1[CH:40]=[CH:39][C:37]([NH2:38])=[CH:36][CH:35]=1>>[CH3:28][C:29]1[NH:33][CH:32]=[N:31][C:30]=1[C:34]1[CH:40]=[CH:39][C:37]([NH:38]/[C:17](=[C:6]2\[C:5](=[O:27])[NH:4][C:12]3[C:7]\2=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH3:16])=[O:14])[CH:11]=3)/[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[CH:36][CH:35]=1

Participants

3

Reactant 2

HCID 235076304-(5-Methyl-1H-imidazol-4-yl)anilineHCID 666859721-Acetyl-3-(1-ethoxy-1-phenylmethylene)-6-methoxycarbonyl-2-indolinone

Product 1

HCID 178497128HCID 178497128, compound

Procedure

Prepared from 1-acetyl-3-(1-ethoxy-1-phenylmethylene)-6-methoxycarbonyl-2-indolinone and 4-(5-methyl-imidazol-4-yl)-aniline Rf value: 0.5 (silica gel, methylene chloride/methanol/ammonia=10:1:0.01) C27H22N4O3

Sources & evidence

ORD record
ord-62cfb47bd46d4218bcbf645fd4b649f8
Source dataset
uspto-grants-2004_07
Patent number
US06762180B1

Reaction notes

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