HCID 23507140, compound → HCID 178497193, compound

HRID 1883864Notes

Reaction equation

HRID 1883864 reaction equation
C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH3:16])=[O:14])[CH:11]=2)[C:6](=[C:17](OCC)[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[C:5]1=[O:27])(=O)C.[C:28]([O:32][C:33]([N:35]1[CH2:40][CH2:39][N:38]([CH2:41][CH2:42][C:43]([N:45]([CH3:53])[C:46]2[CH:51]=[CH:50][C:49]([NH2:52])=[CH:48][CH:47]=2)=[O:44])[CH2:37][CH2:36]1)=[O:34])([CH3:31])([CH3:30])[CH3:29]>>[C:28]([O:32][C:33]([N:35]1[CH2:40][CH2:39][N:38]([CH2:41][CH2:42][C:43]([N:45]([C:46]2[CH:51]=[CH:50][C:49]([NH:52]/[C:17](=[C:6]3\[C:5](=[O:27])[NH:4][C:12]4[C:7]\3=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH3:16])=[O:14])[CH:11]=4)/[C:18]3[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=3)=[CH:48][CH:47]=2)[CH3:53])=[O:44])[CH2:37][CH2:36]1)=[O:34])([CH3:31])([CH3:29])[CH3:30]

Participants

3

Reactant 2

HCID 23507140HCID 23507140, compoundHCID 666859721-Acetyl-3-(1-ethoxy-1-phenylmethylene)-6-methoxycarbonyl-2-indolinone

Product 1

HCID 178497193HCID 178497193, compound

Procedure

Prepared from 1-acetyl-3-(1-ethoxy-1-phenylmethylene)-6-methoxycarbonyl-2-indolinone and N-((2-(4-tert.butoxycarbonyl-piperazin-1-yl)-ethyl)-carbonyl)-N-methyl-p-phenylenediamine Rf value: 0.8 (silica gel, methylene chloride/methanol=5:1) C36H41N5O6

Sources & evidence

ORD record
ord-fe6dc939ae3d4211aab18000f1d8400b
Source dataset
uspto-grants-2004_07
Patent number
US06762180B1

Reaction notes

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