4-[(Azetidin-1-yl)methyl]aniline → HCID 178497136, compound

HRID 1883878Notes

Reaction equation

HRID 1883878 reaction equation
C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH3:16])=[O:14])[CH:11]=2)[C:6](=[C:17](OCC)[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[C:5]1=[O:27])(=O)C.[N:28]1([CH2:32][C:33]2[CH:39]=[CH:38][C:36]([NH2:37])=[CH:35][CH:34]=2)[CH2:31][CH2:30][CH2:29]1>>[N:28]1([CH2:32][C:33]2[CH:39]=[CH:38][C:36]([NH:37]/[C:17](=[C:6]3\[C:5](=[O:27])[NH:4][C:12]4[C:7]\3=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH3:16])=[O:14])[CH:11]=4)/[C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)=[CH:35][CH:34]=2)[CH2:29][CH2:30][CH2:31]1

Participants

3

Reactant 2

HCID 225694404-[(Azetidin-1-yl)methyl]anilineHCID 666859721-Acetyl-3-(1-ethoxy-1-phenylmethylene)-6-methoxycarbonyl-2-indolinone

Product 1

HCID 178497136HCID 178497136, compound

Procedure

Prepared from 1-acetyl-3-(1-ethoxy-1-phenylmethylene)-6-methoxycarbonyl-2-indolinone and 4-(azetidin-1-yl-methyl)-aniline Rf value: 0.5 (silica gel, methylene chloride/methanol/ammonia=9:1:0.5) C27H25N3O3

Sources & evidence

ORD record
ord-c2ca26d883b24e439d7f97f2645f866a
Source dataset
uspto-grants-2004_07
Patent number
US06762180B1

Reaction notes

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