1-Acetyl-3-(1-ethoxy-1-phenylmethylene)-6-methoxycarbonyl-2-indolinone → HCID 178497161, compound

HRID 1883886Notes

Reaction equation

HRID 1883886 reaction equation
C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH3:16])=[O:14])[CH:11]=2)[C:6](=[C:17](OCC)[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[C:5]1=[O:27])(=O)C.NC1C=CC=CC=1.[CH3:35][N:36]([CH3:50])[CH2:37][CH2:38][CH2:39][N:40]([CH2:42][C:43]1[CH:49]=[CH:48][C:46]([NH2:47])=[CH:45][CH:44]=1)[CH3:41]>>[CH3:50][N:36]([CH3:35])[CH2:37][CH2:38][CH2:39][N:40]([CH2:42][C:43]1[CH:44]=[CH:45][C:46]([NH:47]/[C:17](=[C:6]2\[C:5](=[O:27])[NH:4][C:12]3[C:7]\2=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH3:16])=[O:14])[CH:11]=3)/[C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=2)=[CH:48][CH:49]=1)[CH3:41]

Participants

3

Reactant 2

HCID 666859721-Acetyl-3-(1-ethoxy-1-phenylmethylene)-6-methoxycarbonyl-2-indolinoneHCID 131724501HCID 131724501, compound

Product 1

HCID 178497161HCID 178497161, compound

Procedure

Prepared from 1-acetyl-3-(1-ethoxy-1-phenylmethylene)-6-methoxycarbonyl-2-indolinone and 4-((N-(3-dimethylamino-propyl)-N-methyl-amino)-methyl)-aniline aniline Rf value: 0.5 (silica gel, methylene chloride/methanol=9:1) C30H34N4O3

Sources & evidence

ORD record
ord-e888156a33f74cbdb8b311ab6f7c829b
Source dataset
uspto-grants-2004_07
Patent number
US06762180B1

Reaction notes

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