Ammonia → HCID 178513518, compound

HRID 1883896Notes

Reaction equation

HRID 1883896 reaction equation
[Br:1][C:2]1[CH:28]=[CH:27][C:5]([NH:6]/[C:7](=[C:14]2\[C:15](=[O:26])[NH:16][C:17]3[C:22]\2=[CH:21][CH:20]=[C:19]([C:23](O)=[O:24])[CH:18]=3)/[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.[NH3:29]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([NH:6]/[C:7](=[C:14]2\[C:15](=[O:26])[NH:16][C:17]3[C:22]\2=[CH:21][CH:20]=[C:19]([C:23](=[O:24])[NH2:29])[CH:18]=3)/[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=2)=[CH:27][CH:28]=1

Participants

3

Reactant 2

HCID 222AmmoniaHCID 178517304HCID 178517304, compound

Product 1

HCID 178513518HCID 178513518, compound

Procedure

Prepared from 3-Z-[1-(4-bromo-anilino)-1-phenyl-methylene]-6-carboxy-2-indolinone and ammonia Rf value: 0.5 (silica gel, methylene chloride/methanol=10:1) C22H16BrN2O3

Sources & evidence

ORD record
ord-c77e69ae2ea440f1a42cf1bc98b59788
Source dataset
uspto-grants-2004_07
Patent number
US06762180B1

Reaction notes

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