HCID 88057101, compound → HCID 178484415, compound

HRID 1883900Notes

Reaction equation

HRID 1883900 reaction equation
[N:1]1([CH2:7][C:8]2[CH:34]=[CH:33][C:11]([NH:12]/[C:13](=[C:20]3\[C:21](=[O:32])[NH:22][C:23]4[C:28]\3=[CH:27][CH:26]=[C:25]([C:29]([OH:31])=O)[CH:24]=4)/[C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)=[CH:10][CH:9]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.Cl.[CH3:36][NH:37][CH3:38].C(N(C(C)C)CC)(C)C>>[N:1]1([CH2:7][C:8]2[CH:9]=[CH:10][C:11]([NH:12]/[C:13](=[C:20]3\[C:21](=[O:32])[NH:22][C:23]4[C:28]\3=[CH:27][CH:26]=[C:25]([C:29](=[O:31])[N:37]([CH3:38])[CH3:36])[CH:24]=4)/[C:14]3[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=3)=[CH:33][CH:34]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 88057101HCID 88057101, compoundHCID 178517305HCID 178517305, compound

Product 1

HCID 178484415HCID 178484415, compound

Procedure

Prepared from 3-Z-[1-(4-(piperidin-1-yl-methyl)-anilino)-1-phenyl-methylene]-6-carboxy-2-indolinone and dimethylamine hydrochloride/diisopropylethylamine Rf value: 0.5 (silica gel, methylene chloride/methanol=5:1) C30H32N4O2

Sources & evidence

ORD record
ord-5eea0102fc554b5abbf16539d46691f7
Source dataset
uspto-grants-2004_07
Patent number
US06762180B1

Reaction notes

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