N-Methylethylamine → HCID 178464420, compound

HRID 1883901Notes

Reaction equation

HRID 1883901 reaction equation
[N:1]1([CH2:7][C:8]2[CH:34]=[CH:33][C:11]([NH:12]/[C:13](=[C:20]3\[C:21](=[O:32])[NH:22][C:23]4[C:28]\3=[CH:27][CH:26]=[C:25]([C:29]([OH:31])=O)[CH:24]=4)/[C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)=[CH:10][CH:9]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:35]([NH:37][CH3:38])[CH3:36]>>[N:1]1([CH2:7][C:8]2[CH:9]=[CH:10][C:11]([NH:12]/[C:13](=[C:20]3\[C:21](=[O:32])[NH:22][C:23]4[C:28]\3=[CH:27][CH:26]=[C:25]([C:29](=[O:31])[N:37]([CH2:35][CH3:36])[CH3:38])[CH:24]=4)/[C:14]3[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=3)=[CH:33][CH:34]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 12219N-MethylethylamineHCID 178517305HCID 178517305, compound

Product 1

HCID 178464420HCID 178464420, compound

Procedure

Prepared from 3-Z-[1-(4-(piperidin-1-yl-methyl)-anilino)-1-phenyl-methylene]-6-carboxy-2-indolinone and N-ethyl-N-methyl-amine Rf value: 0.5 (aluminium oxide, methylene chloride/ethanol=20:1) C31H34N4O2

Sources & evidence

ORD record
ord-c385ad6780fa4033a1f3b161b8efbaf4
Source dataset
uspto-grants-2004_07
Patent number
US06762180B1

Reaction notes

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