HCID 131724505, compound → HCID 178517302, compound

HRID 1883903Notes

Reaction equation

HRID 1883903 reaction equation
[N:1]1([CH2:7][C:8]2[CH:34]=[CH:33][C:11]([NH:12]/[C:13](=[C:20]3\[C:21](=[O:32])[NH:22][C:23]4[C:28]\3=[CH:27][CH:26]=[C:25]([C:29](O)=[O:30])[CH:24]=4)/[C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)=[CH:10][CH:9]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:35]([CH2:37][NH2:38])[OH:36].C(N(C(C)C)CC)(C)C>>[N:1]1([CH2:7][C:8]2[CH:34]=[CH:33][C:11]([NH:12]/[C:13](=[C:20]3\[C:21](=[O:32])[NH:22][C:23]4[C:28]\3=[CH:27][CH:26]=[C:25]([C:29](=[O:30])[NH:38][CH2:37][CH2:35][OH:36])[CH:24]=4)/[C:14]3[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=3)=[CH:10][CH:9]=2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 131724505HCID 131724505, compoundHCID 178517305HCID 178517305, compound

Product 1

HCID 178517302HCID 178517302, compound

Procedure

Prepared from 3-Z-[1-(4-(piperidin-1-yl-methyl)-anilino)-1-phenyl-methylene]-6-carboxy-2-indolinone and ethanolamine/diisopropylethylamine Rf value: 0.5 (aluminium oxide, methylene chloride/methanol=20:1) C30H32N4O3

Sources & evidence

ORD record
ord-0116cc67f5b14c8c803446c9450865fb
Source dataset
uspto-grants-2004_07
Patent number
US06762180B1

Reaction notes

Loading…