Hydrochloric Acid → HCID 69037856, compound

Participants

Reaction Steps

A mixture of (−)-2-azabicyclo[2.2.1]hept-5-en-3-one (10 g, 91.7 mmol), ethanol (200 mL) and conc. HCl (10 mL) was heated at reflux for 2 h. The mixture was concentrated and the residue dried under vacuum. A white solid was obtained which was suspended in ether to give 17.5 g (100%) of (−)-ethyl cis-4-amino-2-cyclopentene-1-carboxylate hydrochloride.

Provenance & Evidence