HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium benzenethiolate → 5-Chloro-2-phenylsulfanylindan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium benzenethiolate | HCID 4110039 | — |
| Reactant | 2-Bromo-5-chloro-2,3-dihydro-1H-inden-1-one | HCID 11334069 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 5-Chloro-2-phenylsulfanylindan-1-one | HCID 9814142 | — |
Reaction Steps
2.5 g of 2-bromo-5-chloroindan-1-one and 2.8 g of sodium thiophenoxide was suspended in 30 ml of ethanol and heated under reflux for 3 h. The cooled reaction mixture was concentrated and purified chromatographically on silica gel using toluene/ethyl acetate 10/1. This gave 5-chloro-2-phenylsulfanylindan-1-one of melting point 89° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06762326B2 |
| Source dataset | uspto-grants-2004_07 |
| ORD ID | ord-d31d869649df426ca8017e52d8a5f899 |
| Source note | uspto-grants-2004_07 |